It's nice work, but I just don't like the idea behind the story you're putting him in, it doesn't fit his character because he wasn't one to easily give up and turn into a recluse. I do remember Full Throttle being my favorite game as a child, and I even tried to bring it back but my CD won't work on the newer OS's and the freeware rip is shakey at best.
You're also forgetting to elaborate on what happened to Mo, as well as several other characters. Nice work though :]