Quote from OrnateBaboon1 to 16 seems to make the most sense to me, since you can prioritise all of them in order.
Pretty late to dig this up but seeing as this the thread has already been revived maybe someone down the line will benefit:
An element of some maps is to have "random spawns" like Dust2 which give different weighted timings to each site for variety. You can assign multiple spawns the same value so they are equally weighted. Set a basic group of spawns at value 1 for up to 10v10 and any spawns beyond that as 2 so some spawns are only activated when there are a large number of people on the server and still don't get cluttered.